Notícias de: Teaching and Research Center (NEP)

The Pink October campaign – prevention of breast cancer – highlights the importance of an early and effective diagnosis for all audiences. This type of cancer affects 2.2 million women worldwide and, in Brazil, it is responsible for approximately 18 thousand deaths per year. Did you know that IMP has a team of researchers looking for new ways to help diagnose and treat breast cancer patients? The group at the Center for Studies and Research (NEP) has been working to find a more accurate and less invasive diagnosis.

One of the proposals developed at the Laboratory of Translational Research in Oncology at NEP is carried out by doctoral student Thayse Batista, in collaboration with Fiocruz Minas. Thayse is studying the profile of tumor microvesicles present in the blood of breast cancer patients treated at Hospital Luxembourg. These microvesicles are released by the tumor and immune system cells and are present in the blood. According to Thayse, the goal is to develop a diagnosis using microvesicles, which are structures released by the tumor since its formation, when it is still difficult to detect by imaging, making this method less invasive and efficient in detecting the disease and monitoring the treatment .

“The microvesicles carry several characteristic molecules of the tumor, which allows the identification of its origin and communication with other organs. One of the functions of these microvesicles is to allow the tumor to grow and develop in other organs, causing metastasis, as its release reaches other organs through the blood and transforms it into a favorable environment for tumor growth”; explains.

Knowing in depth how the tumor relates to the body is a powerful tool in the fight against breast cancer and providing this type of personalized treatment for SUS patients is an advance in quality health care for all. .

The work developed by Thayse has the collaboration of the clinical team of mastology and oncology, the NEP researchers and the patients who accept to participate in the Center’s research.

Thayse highlights that working closely with breast cancer patients has brought a new perspective to my work. “Meeting these women who face this disease, often with a smile on their faces, inspires me every day to seek more diligently for a service that will make this journey more peaceful and effective.”

*Text written by the Study and Research Center (NEP) team

The Instituto Mário Penna’s Pink October campaign also has important allies to help fight breast cancer. The Teaching and Research Nucleus (NEP) has a team of researchers who are looking for new ways to assist in the diagnosis and treatment of patients, in addition to the imaging exams currently used. This group has been working to find a more accurate diagnosis.

One of the researches developed is part of Thayse Batista’s doctoral project, supervised by researchers Dr. Andréa Teixeira, from the René Rachou Research Institute – FioCruz Minas, and Dr. Letícia Braga, Coordinator of the Oncology Translational Research Laboratory at Instituto Mário Penna. The research assesses the profile of tumor microvesicles present in the blood of patients with breast cancer treated at Hospital Luxemburgo.

According to doctoral student Thayse, the goal is to develop a diagnosis using microvesicles, which are structures released by the tumor since its formation, when detection by imaging is still difficult, making this method more assertive and efficient in detecting the disease and in monitoring of the treatment.

She also explains that the microvesicles carry several characteristic molecules of the tumor, which allow the identification of its origin and communication with other organs. One of the functions of these microvesicles is to allow the tumor to grow and develop in other organs, causing metastasis, transforming it into a favorable environment for tumor growth.

“Our research results show that breast cancer patients have a higher number of microvesicles in their blood when compared to healthy donors. In addition, the profile of these vesicles is different on some occasions, as in the case of patients with metastasis who have a high number of T lymphocyte microvesicles, a cell type already known to be involved in the progression and response to cancer treatment”; explains Dr. Leticia.

The work developed has the collaboration of the clinical team of mastology and oncology, the NEP researchers and the patients who accept to participate. “This has made it possible to go even further in the search for personalized and quality treatment for everyone, following the motto of this year’s campaign at IMP. Knowing in depth how the tumor relates to the body is a powerful tool in the fight against breast cancer and providing this type of personalized treatment for SUS patients is an advance in quality health care for all. ”.